What is Tiagabine Hydrochloride?

CAS: 145821-59-6

Molecular Formula: C20H26ClNO2S2

Molecular weight:412.0089

Tiagabine Hydrochloride is the hydrochloride alkali anatomy of tiagabine, a nipecotic acid acquired with anticonvulsant property. Tiagabine hydrochloride inhibits the gamma-aminobutyric acid (GABA) agent blazon 1 (GAT1), which is predominantly localized in presynaptic terminals of neurons thereby preventing the reuptake of GABA by the presynaptic endings. Consequently, this increases the akin of accessible GABA aural the synaptic cleft, thereby consistent in assiduity of its inhibitory actions. Tiagabine is able adjoin best electroshock seizures and both limbic and ambiguous tonic-clonic seizures.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s