Molecular Formula: C20H26ClNO2S2
Tiagabine Hydrochloride is the hydrochloride alkali anatomy of tiagabine, a nipecotic acid acquired with anticonvulsant property. Tiagabine hydrochloride inhibits the gamma-aminobutyric acid (GABA) agent blazon 1 (GAT1), which is predominantly localized in presynaptic terminals of neurons thereby preventing the reuptake of GABA by the presynaptic endings. Consequently, this increases the akin of accessible GABA aural the synaptic cleft, thereby consistent in assiduity of its inhibitory actions. Tiagabine is able adjoin best electroshock seizures and both limbic and ambiguous tonic-clonic seizures.